- 我们的平台 What is G2H
- 科学原理 The Science of Polygenic Scoring
- 示例报告Sample Report
- 关于遗传检测 More about Genetic Testing
- 常见问题 FAQ
- 产品信息 Product Info
- 公司信息 Company Info
- 服务内容 All services
- 使用咨询 Consult before use
- 售后服务 Customer service
- 遗传咨询 Genetic counselling
- 临床咨询 Clinical counselling
- AI 虚拟咨询师 AI virtual counselling
- 近期活动 Recent activities
- 我们的平台 What is G2H
- 科学原理 The Science of Polygenic Scoring
- 示例报告Sample Report
- 关于遗传检测 More about Genetic Testing
- 常见问题 FAQ
- 产品信息 Product Info
- 公司信息 Company Info
- 服务内容 All services
- 使用咨询 Consult before use
- 售后服务 Customer service
- 遗传咨询 Genetic counselling
- 临床咨询 Clinical counselling
- AI 虚拟咨询师 AI virtual counselling
- 近期活动 Recent activities
什么是多基因风险评分
- 2023-07-27 19:15:00
- unfated 原创
- 3318
- PRS是基于大规模的全基因组关联研究(genome-wide association study,GWAS),通过统计学方法将多个与目标疾病或表型相关的遗传变异(如单核苷酸多态性,SNP)的效应进行加权求和,得到一个数值,反映个体的遗传风险水平。
- PRS的计算方法有多种,主要包括阈值法(threshold method)、剪枝法(pruning method)、贝叶斯法(Bayesian method)等,不同的方法对PRS的准确性和解释性有不同的影响。
- PRS在临床和公共卫生领域有广泛的应用前景,可以用于筛查高风险人群、指导预防和干预措施、优化治疗方案等。目前,PRS已经在一些常见疾病,如心血管疾病、癌症、精神疾病等方面取得了一定的进展。
- PRS的发展还面临一些挑战和局限性,如样本偏倚、遗传异质性、环境因素的影响、伦理法律问题等,需要进一步的研究和探讨。
Gene to Health Limited primarily focuses on developing multi-omics predictive models for common disease risks, conducting biomedical big data analysis and modeling, and providing bioinformatics research services. We are a pioneer in Asia focused on polygenic scoring technology, leveraging millions of disease-related genetic variants and other omics data to predict over 1000 traits and diseases. Our core product suite, G2H, provides personalized health management solutions in one platform, including risk assessments for chronic diseases, dietary optimization, lifestyle advisory, and cancer risk prediction. We aim to revolutionize disease prevention and improve early disease intervention by integrating advanced genomic analysis, ML and AI.
我们是来自香港大学医学院 (HKU Med) 的博士创业团队,拥有以Polygenic Scoring (多基因风险评分,PGS)的核心技术,基因智健(G2H)平台是我们开发的核心产品。该平台主要利用基于多组学大数据的统计机器学习模型分析用户数据,从而预测和评估上千种种人类疾病风险和健康表型,为您的健康人生保驾护航。
联系人: | Dr. CHEN Guolan Lane |
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电话: | +852 46404365 |
Email: | support@gene2h.com |
QQ: | 3028035047 |
微信: | lanechenhku |
微博: | u/7735987435 |
地址: | 1)Unit 707-34, 7F, Building 19W, No. 19 Science Park West Avenue, Hong Kong Science and Technology Park, Pak Shek Kok, N.T., Hong Kong 2)5 Sassoon Road, 1F, Pok Fu Lam, Hong Kong, China 3)Room 903, No. 91, Ke Feng Road, Huangpu District (Guangzhou Development Zone), Guangzhou, Guangdong Province, China 1)中国香港特别行政区新界白石角科技园西大道19号19W座7楼707-34单元 2)中国香港特别行政区薄扶林沙宣道5号1F 3)中国广东省广州市黄埔区(广州开发区)科丰路91号903 |
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